FES antibody (AA 131-180)

Catalog No. ABIN1533592

The Rabbit Polyclonal anti-FES antibody is suitable to detect FES in samples from Human and Mouse. It has been validated for WB, ELISA, IHC and IF.

Quick Overview for FES antibody (AA 131-180) (ABIN1533592)

Target: FES (Feline Sarcoma Oncogene (FES))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FES antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-FES Antibody

Binding Specificity: AA 131-180

Purpose: Fes Antibody

Specificity: Fes Polyclonal Antibody detects endogenous levels of Fes protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human FES. AA range:131-180

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for FES

Target: FES (Feline Sarcoma Oncogene (FES))

Alternative Name: FES

Background:

Synonyms: FES, FPS, Tyrosine-protein kinase Fes/Fps, Feline sarcoma/Fujinami avian sarcoma oncogene homolog, Proto-oncogene c-Fes, Proto-oncogene c-Fps, p93c-fes

Background: This gene encodes the human cellular counterpart of a feline sarcoma retrovirus protein with transforming capabilities. The gene product has tyrosine-specific protein kinase activity and that activity is required for maintenance of cellular transformation. Its chromosomal location has linked it to a specific translocation event identified in patients with acute promyelocytic leukemia but it is also involved in normal hematopoiesis as well as growth factor and cytokine receptor signaling. Alternative splicing results in multiple variants encoding different isoforms.[provided by RefSeq, Jan 2009],

Gene Name: FES

Protein Name: Tyrosine-protein kinase Fes/Fps

Molecular Weight: 93 kDa

Gene ID: 2242

OMIM: 190030

UniProt: P07332

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Signaling Events mediated by VEGFR1 and VEGFR2