TPT1 antibody (AA 71-120)

Catalog No. ABIN1533616

The Rabbit Polyclonal anti-TPT1 antibody is suitable to detect TPT1 in samples from Human, Mouse and Rat. It has been validated for WB, IHC, ELISA and IF.

Quick Overview for TPT1 antibody (AA 71-120) (ABIN1533616)

Target: TPT1 (Tumor Protein, Translationally-Controlled 1 (TPT1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TPT1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Product Details anti-TPT1 Antibody

Binding Specificity: AA 71-120

Purpose: HRF Antibody

Specificity: HRF Polyclonal Antibody detects endogenous levels of HRF protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human TCTP. AA range:71-120

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for TPT1

Target: TPT1 (Tumor Protein, Translationally-Controlled 1 (TPT1))

Alternative Name: TCTP

Background:

Synonyms: TPT1, Translationally-controlled tumor protein, TCTP, Fortilin, Histamine-releasing factor, HRF, p23

Background: function:Involved in calcium binding and microtubule stabilization.,similarity:Belongs to the TCTP family.,subunit:Interacts with STEAP3.,tissue specificity:Found in several healthy and tumoral cells including erythrocytes, hepatocytes, macrophages, platelets, keratinocytes, erythroleukemia cells, gliomas, melanomas, hepatoblastomas, and lymphomas. It cannot be detected in kidney and renal cell carcinoma (RCC). Expressed in placenta and prostate.,

Gene Name: TPT1

Protein Name: Translationally-controlled tumor protein

Molecular Weight: 19 kDa

Gene ID: 7178

OMIM: 600763

UniProt: P13693

Pathways: Response to Water Deprivation, Regulation of Cell Size, Negative Regulation of intrinsic apoptotic Signaling