Hexokinase 1 antibody (AA 31-80)

Catalog No. ABIN1533647

The Rabbit Polyclonal anti-Hexokinase 1 antibody (ABIN1533647) specifically detects Hexokinase 1 in WB, IHC, ELISA and IF. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for Hexokinase 1 antibody (AA 31-80) (ABIN1533647)

Target: Hexokinase 1 (HK1)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Hexokinase 1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Product Details anti-Hexokinase 1 Antibody

Binding Specificity: AA 31-80

Purpose: HXK I Antibody

Specificity: HXK I Polyclonal Antibody detects endogenous levels of HXK I protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human HXK1. AA range:31-80

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for Hexokinase 1

Target: Hexokinase 1 (HK1)

Alternative Name: HXK1

Background:

Synonyms: HK1, Hexokinase-1, Brain form hexokinase, Hexokinase type I, HK I

Background: Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways.This gene encodes a ubiquitous form of hexokinase which localizes to the outer membrane of mitochondria. Mutations in this gene have been associated with hemolytic anemia due to hexokinase deficiency. Alternative splicing of this gene results in several transcript variants which encode different isoforms, some of which are tissue-specific. [provided by RefSeq, Apr 2016],

Gene Name: HK1

Protein Name: Hexokinase-1

Molecular Weight: 102 kDa

Gene ID: 3098

OMIM: 142600

UniProt: P19367

Pathways: Carbohydrate Homeostasis, Warburg Effect