APEX1 antibody (AA 191-240)

Catalog No. ABIN1533681

This Rabbit Polyclonal antibody specifically detects APEX1 in WB and ELISA. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for APEX1 antibody (AA 191-240) (ABIN1533681)

Target: APEX1 (Apurinic/Apyrimidinic Endonuclease 1 (APEX1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This APEX1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-APEX1 Antibody

Binding Specificity: AA 191-240

Specificity:

APEX1 Antibody detects endogenous levels of total APEX1 protein.

Purification: The antibody was purified from rabbit antiserum by affinity-chromatography using immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human APEX1.

Isotype: IgG

Application Details

Application Notes: WB: 1:500~1:1000 ELISA: 1:1000

Comment:

Unigene-Number: Hs.73722 (NCBI Gene Symbol: APEX1)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable at -20°C for at least 1 year.

Expiry Date: 12 months

Target Details for APEX1

Target: APEX1 (Apurinic/Apyrimidinic Endonuclease 1 (APEX1))

Alternative Name: APEX1

Background:

Synonyms: AP endonuclease 1, APE, APE1, APEN, APEX, APEX nuclease, APEX1, APX, DNA-(apurinic or apyrimidinic site) lyase, HAP1, REF-1 protein, REF1

NCBI Gene Symbol: APEX1

Molecular Weight: 35 kDa

Gene ID: 328

OMIM: 107748

UniProt: P27695

Pathways: DNA Damage Repair, Chromatin Binding, Cell RedoxHomeostasis, Smooth Muscle Cell Migration, Positive Regulation of Response to DNA Damage Stimulus