HNF4 alpha/gamma antibody (AA 91-140)

Catalog No. ABIN1533725

The Rabbit Polyclonal anti-HNF4 alpha/gamma antibody (ABIN1533725) specifically detects HNF4 alpha/gamma in WB, ELISA, IHC and IF. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for HNF4 alpha/gamma antibody (AA 91-140) (ABIN1533725)

Target: HNF4 alpha/gamma

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HNF4 alpha/gamma antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-HNF4 alpha/gamma Antibody

Binding Specificity: AA 91-140

Purpose: HNF-4α/γ Antibody

Specificity: HNF-4α/γ Polyclonal Antibody detects endogenous levels of HNF-4α/γ protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human HNF4 alpha/gamma. AA range:91-140

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for HNF4 alpha/gamma

Target: HNF4 alpha/gamma

Background:

Synonyms: HNF4A, HNF4, NR2A1, TCF14, Hepatocyte nuclear factor 4-alpha, HNF-4-alpha, Nuclear receptor subfamily 2 group A member 1, Transcription factor 14, TCF-14, Transcription factor HNF-4, HNF4G, NR2A2, Hepatocyte nuclear factor 4-gamma, HNF-4-ga

Background: The protein encoded by this gene is a nuclear transcription factor which binds DNA as a homodimer. The encoded protein controls the expression of several genes, including hepatocyte nuclear factor 1 alpha, a transcription factor which regulates the expression of several hepatic genes. This gene may play a role in development of the liver, kidney, and intestines. Mutations in this gene have been associated with monogenic autosomal dominant non-insulin-dependent diabetes mellitus type I. Alternative splicing of this gene results in multiple transcript variants encoding several different isoforms. [provided by RefSeq, Apr 2012],

Gene Name: HNF4A/HNF4G

Protein Name: Hepatocyte nuclear factor 4-alpha/gamma

Molecular Weight: 52 kDa

Gene ID: 3172, 3174

OMIM: 125850

UniProt: P41235