GATA4 antibody (AA 271-320)

Catalog No. ABIN1533735

This Rabbit Polyclonal antibody specifically detects GATA4 in WB, ELISA, IHC (p) and IF (p). It exhibits reactivity toward Human, Rat and Mouse.

Quick Overview for GATA4 antibody (AA 271-320) (ABIN1533735)

Target: GATA4 (GATA Binding Protein 4 (GATA4))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GATA4 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-GATA4 Antibody

Binding Specificity: AA 271-320

Purpose: GATA-4 Antibody

Specificity: GATA-4 Polyclonal Antibody detects endogenous levels of GATA-4 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human GATA4. AA range:271-320

Isotype: IgG

Application Details

Application Notes: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/5000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for GATA4

Target: GATA4 (GATA Binding Protein 4 (GATA4))

Alternative Name: GATA4

Background:

Synonyms: GATA4, Transcription factor GATA-4, GATA-binding factor 4

Background: proliferating cell nuclear antigen(PCNA) Homo sapiens The protein encoded by this gene is found in the nucleus and is a cofactor of DNA polymerase delta. The encoded protein acts as a homotrimer and helps increase the processivity of leading strand synthesis during DNA replication. In response to DNA damage, this protein is ubiquitinated and is involved in the RAD6-dependent DNA repair pathway. Two transcript variants encoding the same protein have been found for this gene. Pseudogenes of this gene have been described on chromosome 4 and on the X chromosome. [provided by RefSeq, Jul 2008],

Gene Name: GATA4

Protein Name: Transcription factor GATA-4

Molecular Weight: 44 kDa

OMIM: 600576

UniProt: P43694

Pathways: Peptide Hormone Metabolism, Carbohydrate Homeostasis