CLK1 antibody (AA 101-150)

Catalog No. ABIN1533748

The Rabbit Polyclonal anti-CLK1 antibody is suitable to detect CLK1 in samples from Human and Mouse. It has been validated for WB, ELISA, IHC and IF.

Quick Overview for CLK1 antibody (AA 101-150) (ABIN1533748)

Target: CLK1 (CDC like Kinase 1 (CLK1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CLK1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-CLK1 Antibody

Binding Specificity: AA 101-150

Purpose: CLK1 Antibody

Specificity: CLK1 Polyclonal Antibody detects endogenous levels of CLK1 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human CLK1. AA range:101-150

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for CLK1

Target: CLK1 (CDC like Kinase 1 (CLK1))

Alternative Name: CLK1

Background:

Synonyms: CLK1, CLK, Dual specificity protein kinase CLK1, CDC-like kinase 1

Background: CDC like kinase 1(CLK1) Homo sapiens This gene encodes a member of the CDC2-like (or LAMMER) family of dual specificity protein kinases. In the nucleus, the encoded protein phosphorylates serine/arginine-rich proteins involved in pre-mRNA processing, releasing them into the nucleoplasm. The choice of splice sites during pre-mRNA processing may be regulated by the concentration of transacting factors, including serine/arginine rich proteins. Therefore, the encoded protein may play an indirect role in governing splice site selection. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2009],

Gene Name: CLK1

Protein Name: Dual specificity protein kinase CLK1

Molecular Weight: 57 kDa

Gene ID: 1195

OMIM: 601951

UniProt: P49759