CLK2 antibody (AA 1-50)

Catalog No. ABIN1533749

The Rabbit Polyclonal anti-CLK2 antibody (ABIN1533749) specifically detects CLK2 in WB, ELISA, IHC and IF. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for CLK2 antibody (AA 1-50) (ABIN1533749)

Target: CLK2 (CDC-Like Kinase 2 (CLK2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CLK2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-CLK2 Antibody

Binding Specificity: AA 1-50

Purpose: CLK2 Antibody

Specificity: CLK2 Polyclonal Antibody detects endogenous levels of CLK2 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human CLK2. AA range:1-50

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for CLK2

Target: CLK2 (CDC-Like Kinase 2 (CLK2))

Alternative Name: CLK2

Background:

Synonyms: CLK2, Dual specificity protein kinase CLK2, CDC-like kinase 2

Background: CDC like kinase 2(CLK2) Homo sapiens This gene encodes a dual specificity protein kinase that phosphorylates serine/threonine and tyrosine-containing substrates. Activity of this protein regulates serine- and arginine-rich (SR) proteins of the spliceosomal complex, thereby influencing alternative transcript splicing. Chromosomal translocations have been characterized between this locus and the PAFAH1B3 (platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29 kDa)) gene on chromosome 19, resulting in the production of a fusion protein. Note that this gene is distinct from the TELO2 gene (GeneID:9894), which shares the CLK2 alias, but encodes a protein that is involved in telomere length regulation. There is a pseudogene for this gene on chromosome 7. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2014],

Gene Name: CLK2

Protein Name: Dual specificity protein kinase CLK2

Molecular Weight: 60 kDa

Gene ID: 1196

OMIM: 602989

UniProt: P49760

Pathways: Regulation of Carbohydrate Metabolic Process