Ephrin A5 antibody (AA 31-80)

Catalog No. ABIN1533775

The Rabbit Polyclonal anti-Ephrin A5 antibody is suitable to detect Ephrin A5 in samples from Human, Rat and Mouse. It has been validated for WB, ELISA, IHC and IF.

Quick Overview for Ephrin A5 antibody (AA 31-80) (ABIN1533775)

Target: Ephrin A5 (EFNA5)

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Ephrin A5 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-Ephrin A5 Antibody

Binding Specificity: AA 31-80

Purpose: Ephrin-A5 Antibody

Specificity: Ephrin-A5 Polyclonal Antibody detects endogenous levels of Ephrin-A5 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human EFNA5. AA range:31-80

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:40000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for Ephrin A5

Target: Ephrin A5 (EFNA5)

Alternative Name: EFNA5

Background:

Synonyms: EFNA5, EPLG7, LERK7, Ephrin-A5, AL-1, EPH-related receptor tyrosine kinase ligand 7, LERK-7

Background: Ephrin-A5, a member of the ephrin gene family, prevents axon bundling in cocultures of cortical neurons with astrocytes, a model of late stage nervous system development and differentiation. The EPH and EPH-related receptors comprise the largest subfamily of receptor protein-tyrosine kinases and have been implicated in mediating developmental events, particularly in the nervous system. EPH receptors typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin ligands and receptors have been named by the Eph Nomenclature Committee (1997). Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are similarly divi

Gene Name: EFNA5

Protein Name: Ephrin-A5

Molecular Weight: 26 kDa

Gene ID: 1946

OMIM: 601535

UniProt: P52803

Pathways: RTK Signaling