TFAM antibody (AA 131-180)

Catalog No. ABIN1533816

This Rabbit Polyclonal antibody specifically detects TFAM in WB, IHC, IF and ELISA. It exhibits reactivity toward Human, Mouse, Rat and Cow.

Quick Overview for TFAM antibody (AA 131-180) (ABIN1533816)

Target: TFAM (Transcription Factor A, Mitochondrial (TFAM))

Reactivity: Human, Mouse, Rat, Cow

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TFAM antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA

Product Details anti-TFAM Antibody

Binding Specificity: AA 131-180

Purpose: mtTFA Antibody

Specificity: MtTFA Polyclonal Antibody detects endogenous levels of mtTFA protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human TFAM. AA range:131-180

Isotype: IgG

Application Details

Application Notes: WB 1:500-2000,IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for TFAM

Target: TFAM (Transcription Factor A, Mitochondrial (TFAM))

Alternative Name: TFAM

Background:

Synonyms: TFAM; TCF6; TCF6L2; Transcription factor A; mitochondrial; mtTFA; Mitochondrial transcription factor 1; MtTF1; Transcription factor 6; TCF-6; Transcription factor 6-like 2

Background: This gene encodes a key mitochondrial transcription factor containing two high mobility group motifs. The encoded protein also functions in mitochondrial DNA replication and repair. Sequence polymorphisms in this gene are associated with Alzheimer's and Parkinson's diseases. There are pseudogenes for this gene on chromosomes 6, 7, and 11. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012],

Gene Name: TFAM

Protein Name: Transcription factor A mitochondrial

Molecular Weight: 29 kDa

Gene ID: 7019

OMIM: 600438

UniProt: Q00059

Pathways: Chromatin Binding