MAP3K10 antibody (AA 391-440)

Catalog No. ABIN1533823

The Rabbit Polyclonal anti-MAP3K10 antibody is suitable to detect MAP3K10 in samples from Human and Mouse. It has been validated for IHC, ELISA and IF.

Quick Overview for MAP3K10 antibody (AA 391-440) (ABIN1533823)

Target: MAP3K10 (Mitogen-Activated Protein Kinase Kinase Kinase 10 (MAP3K10))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MAP3K10 antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Product Details anti-MAP3K10 Antibody

Binding Specificity: AA 391-440

Purpose: MLK2 Antibody

Specificity: MLK2 Polyclonal Antibody detects endogenous levels of MLK2 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human MAP3K10. AA range:391-440

Isotype: IgG

Application Details

Application Notes: IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for MAP3K10

Target: MAP3K10 (Mitogen-Activated Protein Kinase Kinase Kinase 10 (MAP3K10))

Alternative Name: MAP3K10

Background:

Synonyms: MAP3K10, MLK2, MST, Mitogen-activated protein kinase kinase kinase 10, Mixed lineage kinase 2, Protein kinase MST

Background: The protein encoded byThis gene is a member of the serine/threonine kinase family. This kinase has been shown to activate MAPK8/JNK and MKK4/SEK1, and this kinase itself can be phoshorylated, and thus activated by JNK kinases. This kinase functions preferentially on the JNK signaling pathway, and is reported to be involved in nerve growth factor (NGF) induced neuronal apoptosis. [provided by RefSeq, Jul 2008],

Gene Name: MAP3K10

Protein Name: Mitogen-activated protein kinase kinase kinase 10

Molecular Weight: 103 kDa

Gene ID: 4294

OMIM: 600137

UniProt: Q02779