ZFHX3 antibody (AA 761-810)

Catalog No. ABIN1533928

The Rabbit Polyclonal anti-ZFHX3 antibody is suitable to detect ZFHX3 in samples from Human and Mouse. It has been validated for ELISA, IHC and IF.

Quick Overview for ZFHX3 antibody (AA 761-810) (ABIN1533928)

Target: ZFHX3 (Zinc Finger Homeobox 3 (ZFHX3))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ZFHX3 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-ZFHX3 Antibody

Binding Specificity: AA 761-810

Purpose: ATBF1 Antibody

Specificity: ATBF1 Polyclonal Antibody detects endogenous levels of ATBF1 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human ZFHX3. AA range:761-810

Isotype: IgG

Application Details

Application Notes: IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for ZFHX3

Target: ZFHX3 (Zinc Finger Homeobox 3 (ZFHX3))

Alternative Name: ZFHX3

Background:

Synonyms: ZFHX3, ATBF1, Zinc finger homeobox protein 3, AT motif-binding factor, AT-binding transcription factor 1, Alpha-fetoprotein enhancer-binding protein, Zinc finger homeodomain protein 3, ZFH-3

Background: This gene encodes a transcription factor with multiple homeodomains and zinc finger motifs, and regulates myogenic and neuronal differentiation. The encoded protein suppresses expression of the alpha-fetoprotein gene by binding to an AT-rich enhancer motif. The protein has also been shown to negatively regulate c-Myb, and transactivate the cell cycle inhibitor cyclin-dependent kinase inhibitor 1A (also known as p21CIP1). This gene is reported to function as a tumor suppressor in several cancers, and sequence variants of this gene are also associated with atrial fibrillation. Multiple transcript variants expressed from alternate promoters and encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009],

Gene Name: ZFHX3

Protein Name: Zinc finger homeobox protein 3

Molecular Weight: 404 kDa

Gene ID: 463

OMIM: 104155

UniProt: Q15911

Pathways: Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development