CDKN3 antibody (AA 31-80)

Catalog No. ABIN1533933

This Rabbit Polyclonal antibody specifically detects CDKN3 in WB, IHC, ELISA and IF. It exhibits reactivity toward Human and Mouse.

Quick Overview for CDKN3 antibody (AA 31-80) (ABIN1533933)

Target: CDKN3 (Cyclin-Dependent Kinase Inhibitor 3 (CDKN3))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CDKN3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Product Details anti-CDKN3 Antibody

Binding Specificity: AA 31-80

Purpose: CDKN3 Antibody

Specificity: CDKN3 Polyclonal Antibody detects endogenous levels of CDKN3 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human CDKN3. AA range:31-80

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for CDKN3

Target: CDKN3 (Cyclin-Dependent Kinase Inhibitor 3 (CDKN3))

Alternative Name: CDKN3

Background:

Synonyms: CDKN3, CDI1, CIP2, KAP, Cyclin-dependent kinase inhibitor 3, CDK2-associated dual-specificity phosphatase, Cyclin-dependent kinase interactor 1, Cyclin-dependent kinase-interacting protein 2, Kinase-associated phosphatase

Background: The protein encoded by this gene belongs to the dual specificity protein phosphatase family. It was identified as a cyclin-dependent kinase inhibitor, and has been shown to interact with, and dephosphorylate CDK2 kinase, thus prevent the activation of CDK2 kinase. This gene was reported to be deleted, mutated, or overexpressed in several kinds of cancers. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008],

Gene Name: CDKN3

Protein Name: Cyclin-dependent kinase inhibitor 3

Molecular Weight: 23 kDa

Gene ID: 1033

OMIM: 123832

UniProt: Q16667