ANO1 antibody (AA 921-970)

Catalog No. ABIN1533954

This Rabbit Polyclonal antibody specifically detects ANO1 in IF and ELISA. It exhibits reactivity toward Human and Mouse.

Quick Overview for ANO1 antibody (AA 921-970) (ABIN1533954)

Target: ANO1 (Anoctamin 1, Calcium Activated Chloride Channel (ANO1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ANO1 antibody is un-conjugated

Application: Immunofluorescence (IF), ELISA

Product Details anti-ANO1 Antibody

Binding Specificity: AA 921-970

Purpose: TMEM16A Antibody

Specificity: TMEM16A Polyclonal Antibody detects endogenous levels of TMEM16A protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human TM16A. AA range:921-970

Isotype: IgG

Application Details

Application Notes: IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for ANO1

Target: ANO1 (Anoctamin 1, Calcium Activated Chloride Channel (ANO1))

Background:

Synonyms: ANO1, DOG1, ORAOV2, TAOS2, TMEM16A, Anoctamin-1, Discovered on gastrointestinal stromal tumors protein 1, Oral cancer overexpressed protein 2, Transmembrane protein 16A, Tumor-amplified and overexpressed sequence 2

Background: domain:The region spanning the fifth and sixth transmembrane domains probably forms the pore-forming region.,function:Acts as a calcium-activated chloride channel. Required for normal tracheal development.,similarity:Belongs to the anoctamin family.,tissue specificity:Broadly expressed with higher levels in liver and skeletal muscle.,

Gene Name: ANO1

Protein Name: Anoctamin-1

Molecular Weight: 114 kDa

Gene ID: 55107

OMIM: 610108

UniProt: Q5XXA6