KAT2A antibody (AA 691-740)

Catalog No. ABIN1534045

The Rabbit Polyclonal anti-KAT2A antibody is suitable to detect KAT2A in samples from Human and Mouse. It has been validated for WB, ELISA, IHC and IF.

Quick Overview for KAT2A antibody (AA 691-740) (ABIN1534045)

Target: KAT2A (K(lysine) Acetyltransferase 2A (KAT2A))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KAT2A antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-KAT2A Antibody

Binding Specificity: AA 691-740

Purpose: GCN5 Antibody

Specificity: GCN5 Polyclonal Antibody detects endogenous levels of GCN5 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human GCN5L2. AA range:691-740

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for KAT2A

Target: KAT2A (K(lysine) Acetyltransferase 2A (KAT2A))

Alternative Name: GCN5L2

Background:

Synonyms: KAT2A, GCN5, GCN5L2, HGCN5, Histone acetyltransferase KAT2A, General control of amino acid synthesis protein 5-like 2, Histone acetyltransferase GCN5, HsGCN5, Lysine acetyltransferase 2A, STAF97

Background: KAT2A, or GCN5, is a histone acetyltransferase (HAT) that functions primarily as a transcriptional activator. It also functions as a repressor of NF-kappa-B (see MIM 164011) by promoting ubiquitination of the NF-kappa-B subunit RELA (MIM 164014) in a HAT-independent manner (Mao et al., 2009 [PubMed 19339690]).[supplied by OMIM, Sep 2009],

Gene Name: KAT2A

Protein Name: Histone acetyltransferase KAT2A

Molecular Weight: 93 kDa

Gene ID: 2648

OMIM: 602301

UniProt: Q92830

Pathways: Chromatin Binding, Tube Formation