NT5C3 antibody (AA 11-60)

Catalog No. ABIN484737

The Rabbit Polyclonal anti-NT5C3 antibody (ABIN484737) specifically detects NT5C3 in WB, IHC, ELISA and IF. The antibody is reactive with Human and Mouse samples.

Quick Overview for NT5C3 antibody (AA 11-60) (ABIN484737)

Target: NT5C3 (5'-Nucleotidase, Cytosolic III (NT5C3))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NT5C3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Product Details anti-NT5C3 Antibody

Binding Specificity: AA 11-60

Purpose: NT5C3 Antibody

Specificity: NT5C3 Polyclonal Antibody detects endogenous levels of NT5C3 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human NT5C3. AA range:11-60

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:40000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for NT5C3

Target: NT5C3 (5'-Nucleotidase, Cytosolic III (NT5C3))

Alternative Name: NT5C3

Background:

Synonyms: NT5C3; P5N1; UMPH1; HSPC233; Cytosolic 5'-nucleotidase 3; Cytosolic 5'-nucleotidase III; cN-III; Pyrimidine 5'-nucleotidase 1; P5'N-1; P5N-1; PN-I; Uridine 5'-monophosphate hydrolase 1; p36

Background: 5'-nucleotidase, cytosolic IIIA(NT5C3A) Homo sapiens This gene encodes a member of the 5'-nucleotidase family of enzymes that catalyze the dephosphorylation of nucleoside 5'-monophosphates. The encoded protein is the type 1 isozyme of pyrimidine 5' nucleotidase and catalyzes the dephosphorylation of pyrimidine 5' monophosphates. Mutations in this gene are a cause of hemolytic anemia due to uridine 5-prime monophosphate hydrolase deficiency. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and pseudogenes of this gene are located on the long arm of chromosomes 3 and 4. [provided by RefSeq, Mar 2012],

Gene Name: NT5C3

Protein Name: Cytosolic 5'-nucleotidase 3

Molecular Weight: 37 kDa

Gene ID: 51251

OMIM: 606224

UniProt: Q9H0P0