Serotonin Receptor 2B antibody (AA 261-310)

Catalog No. ABIN1534243

The Rabbit Polyclonal anti-Serotonin Receptor 2B antibody is suitable to detect Serotonin Receptor 2B in samples from Human, Rat and Mouse. It has been validated for WB, ELISA, IF, IHC (p) and ICC.

Quick Overview for Serotonin Receptor 2B antibody (AA 261-310) (ABIN1534243)

Target: Serotonin Receptor 2B (HTR2B) (5-Hydroxytryptamine (serotonin) Receptor 2B (HTR2B))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Serotonin Receptor 2B antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)

Product Details anti-Serotonin Receptor 2B Antibody

Binding Specificity: AA 261-310

Purpose: SR-2B Antibody

Specificity: SR-2B Polyclonal Antibody detects endogenous levels of SR-2B protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human 5-HT-2B. AA range:261-310

Isotype: IgG

Application Details

Application Notes: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for Serotonin Receptor 2B

Target: Serotonin Receptor 2B (HTR2B) (5-Hydroxytryptamine (serotonin) Receptor 2B (HTR2B))

Alternative Name: 5-HT-2B

Background:

Synonyms: HTR2B, 5-hydroxytryptamine receptor 2B, 5-HT-2B, 5-HT2B, Serotonin receptor 2B

Background: Lysine methylation occurs in three distinct states, having either one (me1), two (me2) or three (me3) methyl groups attached to the amine group of the lysine side chain. In eukaryotes, histone H3 trimethylated at lysine 4 (H3K4me3) is associated with active chromatin and gene expression.

Gene Name: HTR2B

Protein Name: 5-hydroxytryptamine receptor 2B

Molecular Weight: 54 kDa

OMIM: 601122

UniProt: P41595

Pathways: JAK-STAT Signaling, Inositol Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling, Regulation of Carbohydrate Metabolic Process