ADCY1 antibody (AA 231-280)

Catalog No. ABIN1534252

The Rabbit Polyclonal anti-ADCY1 antibody is suitable to detect ADCY1 in samples from Human and Mouse. It has been validated for WB, ELISA, IHC and IF.

Quick Overview for ADCY1 antibody (AA 231-280) (ABIN1534252)

Target: ADCY1 (Adenylate Cyclase 1 (Brain) (ADCY1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ADCY1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-ADCY1 Antibody

Binding Specificity: AA 231-280

Purpose: A Cyclase I Antibody

Specificity: A Cyclase I Polyclonal Antibody detects endogenous levels of A Cyclase I protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human ADCY1. AA range:231-280

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for ADCY1

Target: ADCY1 (Adenylate Cyclase 1 (Brain) (ADCY1))

Alternative Name: ADCY1

Background:

Synonyms: ADCY1, Adenylate cyclase type 1, ATP pyrophosphate-lyase 1, Adenylate cyclase type I, Adenylyl cyclase 1, Ca(2+)/calmodulin-activated adenylyl cyclase

Background: This gene encodes a member of the of adenylate cyclase gene family that is primarily expressed in the brain. This protein is regulated by calcium/calmodulin concentration and may be involved in brain development. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013],

Gene Name: ADCY1

Protein Name: Adenylate cyclase type 1

Molecular Weight: 123 kDa

Gene ID: 107

OMIM: 103072

UniProt: Q08828

Pathways: EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Thyroid Hormone Synthesis, cAMP Metabolic Process, Myometrial Relaxation and Contraction, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma