ADCY4 antibody (AA 195-244)

Catalog No. ABIN1534253

The Rabbit Polyclonal anti-ADCY4 antibody (ABIN1534253) specifically detects ADCY4 in WB and ELISA. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for ADCY4 antibody (AA 195-244) (ABIN1534253)

Target: ADCY4 (Adenylate Cyclase 4 (ADCY4))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ADCY4 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-ADCY4 Antibody

Binding Specificity: AA 195-244

Purpose: A Cyclase IV Antibody

Specificity: A Cyclase IV Polyclonal Antibody detects endogenous levels of A Cyclase IV protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human ADCY4. AA range:195-244

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. ELISA: 1:20000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for ADCY4

Target: ADCY4 (Adenylate Cyclase 4 (ADCY4))

Alternative Name: ADCY4

Background:

Synonyms: ADCY4, Adenylate cyclase type 4, ATP pyrophosphate-lyase 4, Adenylate cyclase type IV, Adenylyl cyclase 4

Background: This gene encodes a member of the family of adenylate cyclases, which are membrane-associated enzymes that catalyze the formation of the secondary messenger cyclic adenosine monophosphate (cAMP). Mouse studies show that adenylate cyclase 4, along with adenylate cyclases 2 and 3, is expressed in olfactory cilia, suggesting that several different adenylate cyclases may couple to olfactory receptors and that there may be multiple receptor-mediated mechanisms for the generation of cAMP signals. Alternative splicing results in transcript variants. [provided by RefSeq, Nov 2010],

Gene Name: ADCY4

Protein Name: Adenylate cyclase type 4

Molecular Weight: 119 kDa

Gene ID: 196883

OMIM: 600292

UniProt: Q8NFM4

Pathways: EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Thyroid Hormone Synthesis, cAMP Metabolic Process, Myometrial Relaxation and Contraction, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma