Cadherin 13 antibody (AA 331-380)

Catalog No. ABIN1534283

The Rabbit Polyclonal anti-Cadherin 13 antibody (ABIN1534283) specifically detects Cadherin 13 in WB, IHC, ELISA and IF. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for Cadherin 13 antibody (AA 331-380) (ABIN1534283)

Target: Cadherin 13 (CDH13)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Cadherin 13 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Product Details anti-Cadherin 13 Antibody

Binding Specificity: AA 331-380

Purpose: T-cadherin Antibody

Specificity: T-cadherin Polyclonal Antibody detects endogenous levels of T-cadherin protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human CDH13. AA range:331-380

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for Cadherin 13

Target: Cadherin 13 (CDH13)

Alternative Name: CDH13

Background:

Synonyms: CDH13, CDHH, Cadherin-13, Heart cadherin, H-cadherin, P105, Truncated cadherin, T-cad, T-cadherin

Background: This gene encodes a member of the cadherin superfamily. The encoded protein is localized to the surface of the cell membrane and is anchored by a GPI moiety, rather than by a transmembrane domain. The protein lacks the cytoplasmic domain characteristic of other cadherins, and so is not thought to be a cell-cell adhesion glycoprotein. This protein acts as a negative regulator of axon growth during neural differentiation. It also protects vascular endothelial cells from apoptosis due to oxidative stress, and is associated with resistance to atherosclerosis. The gene is hypermethylated in many types of cancer. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, May 2011],

Gene Name: CDH13

Protein Name: Cadherin-13

Molecular Weight: 78 kDa

Gene ID: 1012

OMIM: 601364

UniProt: P55290

Pathways: EGFR Signaling Pathway, Cell-Cell Junction Organization