PMS1 antibody (AA 441-490)

Catalog No. ABIN1534483

The Rabbit Polyclonal anti-PMS1 antibody is suitable to detect PMS1 in samples from Human, Rat and Mouse. It has been validated for WB, ELISA, IHC and IF.

Quick Overview for PMS1 antibody (AA 441-490) (ABIN1534483)

Target: PMS1 (PMS1 Postmeiotic Segregation Increased 1 (S. Cerevisiae) (PMS1))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PMS1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-PMS1 Antibody

Binding Specificity: AA 441-490

Purpose: PMS1 Antibody

Specificity: PMS1 Polyclonal Antibody detects endogenous levels of PMS1 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human PMS1. AA range:441-490

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for PMS1

Target: PMS1 (PMS1 Postmeiotic Segregation Increased 1 (S. Cerevisiae) (PMS1))

Alternative Name: PMS1

Background:

Synonyms: PMS1, PMSL1, PMS1 protein homolog 1, DNA mismatch repair protein PMS1

Background: This gene encodes a protein belonging to the DNA mismatch repair mutL/hexB family. This protein is thought to be involved in the repair of DNA mismatches, and it can form heterodimers with MLH1, a known DNA mismatch repair protein. Mutations in this gene cause hereditary nonpolyposis colorectal cancer type 3 (HNPCC3) either alone or in combination with mutations in other genes involved in the HNPCC phenotype, which is also known as Lynch syndrome. [provided by RefSeq, Jul 2008],

Gene Name: PMS1

Protein Name: PMS1 protein homolog 1

Molecular Weight: 105 kDa

Gene ID: 5378

OMIM: 600258

UniProt: P54277