MRPS17 antibody (AA 11-60)

Catalog No. ABIN1534506

This Rabbit Polyclonal antibody specifically detects MRPS17 in WB, ELISA, IHC and IF. It exhibits reactivity toward Human and Mouse.

Quick Overview for MRPS17 antibody (AA 11-60) (ABIN1534506)

Target: MRPS17 (Mitochondrial Ribosomal Protein S17 (MRPS17))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MRPS17 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-MRPS17 Antibody

Binding Specificity: AA 11-60

Purpose: MRP-S17 Antibody

Specificity: MRP-S17 Polyclonal Antibody detects endogenous levels of MRP-S17 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human MRPS17. AA range:11-60

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for MRPS17

Target: MRPS17 (Mitochondrial Ribosomal Protein S17 (MRPS17))

Alternative Name: MRPS17

Background:

Synonyms: MRPS17, RPMS17, HSPC011, 28S ribosomal protein S17, mitochondrial, MRP-S17, S17mt

Background: Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75 % protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology.This gene encodes a 28S subunit protein that belongs to the ribosomal protein S17P family. The encoded protein is moderately conserved between human mitochondrial and prokaryotic ribosomal proteins. Pseudogenes corresponding to this gene are found

Gene Name: MRPS17

Protein Name: 28S ribosomal protein S17 mitochondrial

Molecular Weight: 14 kDa

Gene ID: 51373

OMIM: 611980

UniProt: Q9Y2R5