MRPS17 antibody (AA 30-110)

Catalog No. ABIN7223020

This Rabbit Polyclonal antibody specifically detects MRPS17 in WB, ELISA, IHC and IF. It exhibits reactivity toward Human and Mouse.

Quick Overview for MRPS17 antibody (AA 30-110) (ABIN7223020)

Target: MRPS17 (Mitochondrial Ribosomal Protein S17 (MRPS17))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MRPS17 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-MRPS17 Antibody

Binding Specificity: AA 30-110

Purpose: Rabbit Anti-MRP-S17 Polyclonal Antibody

Specificity: MRP-S17 Polyclonal Antibody detects endogenous levels of MRP-S17 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the N-terminal region of human MRP-S17 at AA range: 30-110

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,ELISA 1:40000,IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for MRPS17

Target: MRPS17 (Mitochondrial Ribosomal Protein S17 (MRPS17))

Alternative Name: MRP-S17

Background: MRPS17, RPMS17, HSPC011, 28S ribosomal protein S17, mitochondrial, MRP-S17, S17mtMammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75 % protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. MRPS17 (mitochondrial ribosomal protein S17) encodes a 28S subunit protein that belongs to the ribosomal protein S17P family. The encoded protein is moderately conserved between human mitochondrial and prokaryotic ribosomal proteins. Pseudogenes corresponding to MRPS17 are found on chromosomes 1p, 3p, 6q, 14p, 18q, and Xq.

Molecular Weight: 22kD

Gene ID: 51373

UniProt: Q9Y2R5