MRPS18A antibody (AA 81-130)

Catalog No. ABIN1534507

The Rabbit Polyclonal anti-MRPS18A antibody is suitable to detect MRPS18A in samples from Human, Mouse and Rat. It has been validated for ELISA, IHC and IF.

Quick Overview for MRPS18A antibody (AA 81-130) (ABIN1534507)

Target: MRPS18A (Mitochondrial Ribosomal Protein S18A (MRPS18A))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MRPS18A antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-MRPS18A Antibody

Binding Specificity: AA 81-130

Purpose: MRP-S18A Antibody

Specificity: MRP-S18A Polyclonal Antibody detects endogenous levels of MRP-S18A protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human MRPS18A. AA range:81-130

Isotype: IgG

Application Details

Application Notes: IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for MRPS18A

Target: MRPS18A (Mitochondrial Ribosomal Protein S18A (MRPS18A))

Alternative Name: MRPS18A

Background:

Synonyms: MRPS18A, 28S ribosomal protein S18a, mitochondrial, MRP-S18-a, Mrps18a, S18mt-a, 28S ribosomal protein S18-3, mitochondrial, MRP-S18-3

Background: Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75 % protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology.This gene encodes a 28S subunit protein that belongs to the ribosomal protein S18P family. The encoded protein is one of three that has significant sequence similarity to bacterial S18 proteins. The primary sequences of the three human mitochondria

Gene Name: MRPS18A

Protein Name: 28S ribosomal protein S18a mitochondrial

Molecular Weight: 22 kDa

Gene ID: 55168

OMIM: 611981

UniProt: Q9NVS2