MRPS18C antibody (AA 71-120)

Catalog No. ABIN1534508

The Rabbit Polyclonal anti-MRPS18C antibody (ABIN1534508) specifically detects MRPS18C in ELISA, WB, IHC and IF. The antibody is reactive with Human and Mouse samples.

Quick Overview for MRPS18C antibody (AA 71-120) (ABIN1534508)

Target: MRPS18C (Mitochondrial Ribosomal Protein S18C (MRPS18C))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MRPS18C antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-MRPS18C Antibody

Binding Specificity: AA 71-120

Purpose: MRP-S18C Antibody

Specificity: MRP-S18C Polyclonal Antibody detects endogenous levels of MRP-S18C protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human MRPS18C. AA range:71-120

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:40000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for MRPS18C

Target: MRPS18C (Mitochondrial Ribosomal Protein S18C (MRPS18C))

Alternative Name: MRPS18C

Background:

Synonyms: MRPS18C, CGI-134, 28S ribosomal protein S18c, mitochondrial, MRP-S18-c, Mrps18-c, S18mt-c, 28S ribosomal protein S18-1, mitochondrial, MRP-S18-1

Background: Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75 % protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology.This gene encodes a 28S subunit protein that belongs to the ribosomal protein S18P family. The encoded protein is one of three that has significant sequence similarity to bacterial S18 proteins. The primary sequences of the three human mitochondria

Gene Name: MRPS18C

Protein Name: 28S ribosomal protein S18c mitochondrial

Molecular Weight: 15 kDa

Gene ID: 51023

OMIM: 611983

UniProt: Q9Y3D5