MRPL10 antibody (AA 211-260)

Catalog No. ABIN1534515

This Rabbit Polyclonal antibody specifically detects MRPL10 in WB, ELISA, IHC and IF. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for MRPL10 antibody (AA 211-260) (ABIN1534515)

Target: MRPL10 (Mitochondrial Ribosomal Protein L10 (MRPL10))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MRPL10 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-MRPL10 Antibody

Binding Specificity: AA 211-260

Purpose: MRP-L10 Antibody

Specificity: MRP-L10 Polyclonal Antibody detects endogenous levels of MRP-L10 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human MRPL10. AA range:211-260

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for MRPL10

Target: MRPL10 (Mitochondrial Ribosomal Protein L10 (MRPL10))

Alternative Name: MRPL10

Background:

Synonyms: MRPL10, MRPL8, RPML8, 39S ribosomal protein L10, mitochondrial, L10mt, MRP-L10, 39S ribosomal protein L8, mitochondrial, L8mt, MRP-L8

Background: Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75 % protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology.This gene encodes a 39S subunit protein. Sequence analysis identified three transcript variants that encode two different isoforms. A pseudogene corresponding to this gene is found on chromosome 5q. [provided by RefSeq, Nov 2010],

Gene Name: MRPL10

Protein Name: 39S ribosomal protein L10 mitochondrial

Molecular Weight: 29 kDa

Gene ID: 124995

OMIM: 611825

UniProt: Q7Z7H8