MRPL12 antibody (AA 31-80)

Catalog No. ABIN1534517

The Rabbit Polyclonal anti-MRPL12 antibody (ABIN1534517) specifically detects MRPL12 in WB, ELISA and IHC. The antibody is reactive with Human and Mouse samples.

Quick Overview for MRPL12 antibody (AA 31-80) (ABIN1534517)

Target: MRPL12 (Mitochondrial Ribosomal Protein L12 (MRPL12))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MRPL12 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-MRPL12 Antibody

Binding Specificity: AA 31-80

Purpose: MRP-L12 Antibody

Specificity: MRP-L12 Polyclonal Antibody detects endogenous levels of MRP-L12 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human MRPL12. AA range:31-80

Isotype: IgG

Application Details

Application Notes: WB 1:500-2000,IHC 1:50-300, ELISA 2000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for MRPL12

Target: MRPL12 (Mitochondrial Ribosomal Protein L12 (MRPL12))

Alternative Name: MRPL12

Background:

Synonyms: MRPL12, RPML12, 39S ribosomal protein L12, mitochondrial, L12mt, MRP-L12, 5c5-2

Background: Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75 % protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology.This gene encodes a 39S subunit protein which forms homodimers. In prokaryotic ribosomes, two L7/L12 dimers and one L10 protein form the L8 protein complex. [provided by RefSeq, Jul 2008],

Gene Name: MRPL12

Protein Name: 39S ribosomal protein L12 mitochondrial

Molecular Weight: 21 kDa

Gene ID: 6182

OMIM: 602375

UniProt: P52815