MRPL47 antibody (AA 191-240)

Catalog No. ABIN1534533

This Rabbit Polyclonal antibody specifically detects MRPL47 in WB and IHC. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for MRPL47 antibody (AA 191-240) (ABIN1534533)

Target: MRPL47 (Mitochondrial Ribosomal Protein L47 (MRPL47))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MRPL47 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-MRPL47 Antibody

Binding Specificity: AA 191-240

Purpose: MRP-L47 Antibody

Specificity: MRP-L47 Polyclonal Antibody detects endogenous levels of MRP-L47 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human MRPL47. AA range:191-240

Isotype: IgG

Application Details

Application Notes: WB 1:500-2000,IHC 1:50-300

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for MRPL47

Target: MRPL47 (Mitochondrial Ribosomal Protein L47 (MRPL47))

Alternative Name: MRPL47

Background:

Synonyms: MRPL47, NCM1, CGI-204, 39S ribosomal protein L47, mitochondrial, L47mt, MRP-L47, Nasopharyngeal carcinoma metastasis-related protein 1

Background: Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75 % protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology.This gene encodes a 39S subunit protein. This gene is immediately adjacent to the gene for BAF complex 53 kDa subunit protein a (BAF53a), in a tail-to-tail orientation. Two transcript variants encoding different protein isoforms have been identifie

Gene Name: MRPL47

Protein Name: 39S ribosomal protein L47 mitochondrial

Molecular Weight: 29 kDa

Gene ID: 57129

OMIM: 611852

UniProt: Q9HD33