C9orf89 antibody (AA 21-70)

Catalog No. ABIN1534683

This Rabbit Polyclonal antibody specifically detects C9orf89 in ELISA, IHC and IF. It exhibits reactivity toward Human and Mouse.

Quick Overview for C9orf89 antibody (AA 21-70) (ABIN1534683)

Target: C9orf89 (Chromosome 9 Open Reading Frame 89 (C9orf89))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This C9orf89 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-C9orf89 Antibody

Binding Specificity: AA 21-70

Purpose: BinCARD Antibody

Specificity: BinCARD Polyclonal Antibody detects endogenous levels of BinCARD protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human C9orf89. AA range:21-70

Isotype: IgG

Application Details

Application Notes: IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for C9orf89

Target: C9orf89 (Chromosome 9 Open Reading Frame 89 (C9orf89))

Alternative Name: C9orf89

Background:

Synonyms: C9orf89, Bcl10-interacting CARD protein, BinCARD

Background: function:Plays a role in inhibiting the effects of BCL10-induced activation of NF-kappa-B. May inhibit the phosphorylation of BCL10 in a CARD-dependent manner.,PTM:Isoform 2 is phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Contains 1 CARD domain.,subcellular location:Co-expression with BCL10 induced translocation from nucleus to cytosol.,subunit:Associates with BCL10 by CARD-CARD interaction.,tissue specificity:Expressed in ovary, testis, placenta, skeletal muscle, kidney, lung, heart and liver (at protein level). Expressed in thymus and brain.,

Gene Name: C9orf89

Protein Name: Bcl10-interacting CARD protein

Molecular Weight: 25 kDa

Gene ID: 84270

UniProt: Q96LW7