Claudin 19 antibody (AA 81-130)

Catalog No. ABIN1534781

The Rabbit Polyclonal anti-Claudin 19 antibody (ABIN1534781) specifically detects Claudin 19 in WB and ELISA. The antibody is reactive with Human and Rat samples.

Quick Overview for Claudin 19 antibody (AA 81-130) (ABIN1534781)

Target: Claudin 19 (CLDN19)

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Claudin 19 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-Claudin 19 Antibody

Binding Specificity: AA 81-130

Purpose: Claudin-19 Antibody

Specificity: Claudin-19 Polyclonal Antibody detects endogenous levels of Claudin-19 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human CLDN19. AA range:81-130

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for Claudin 19

Target: Claudin 19 (CLDN19)

Alternative Name: CLDN19

Background:

Synonyms: CLDN19, Claudin-19

Background: The product of this gene belongs to the claudin family. It plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity. Defects in this gene are the cause of hypomagnesemia renal with ocular involvement (HOMGO). HOMGO is a progressive renal disease characterized by primary renal magnesium wasting with hypomagnesemia, hypercalciuria and nephrocalcinosis associated with severe ocular abnormalities such as bilateral chorioretinal scars, macular colobomata, significant myopia and nystagmus. Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jun 2010],

Gene Name: CLDN19

Protein Name: Claudin-19

Molecular Weight: 23 kDa

Gene ID: 149461

OMIM: 610036

UniProt: Q8N6F1

Pathways: Cell-Cell Junction Organization, Hepatitis C