GARP antibody (AA 571-620)

Catalog No. ABIN1534805

The Rabbit Polyclonal anti-GARP antibody (ABIN1534805) specifically detects GARP in WB and ELISA. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for GARP antibody (AA 571-620) (ABIN1534805)

Target: GARP (CNGB1) (Cyclic Nucleotide Gated Channel beta 1 (CNGB1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GARP antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-GARP Antibody

Binding Specificity: AA 571-620

Purpose: CNG-1β Antibody

Specificity: CNG-1β Polyclonal Antibody detects endogenous levels of CNG-1β protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human CNGB1. AA range:571-620

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for GARP

Target: GARP (CNGB1) (Cyclic Nucleotide Gated Channel beta 1 (CNGB1))

Alternative Name: CNGB1

Background:

Synonyms: CNGB1, CNCG2, CNCG3L, CNCG4, RCNC2, Cyclic nucleotide-gated cation channel beta-1, Cyclic nucleotide-gated cation channel 4, CNG channel 4, CNG-4, CNG4, Cyclic nucleotide-gated cation channel gamma, Cyclic nucleotide-gated cation channel mo

Background: In humans, the rod photoreceptor cGMP-gated cation channel helps regulate ion flow into the rod photoreceptor outer segment in response to light-induced alteration of the levels of intracellular cGMP. This channel consists of two subunits, alpha and beta, withThe protein encoded by this gene representing the beta subunit. Defects in this gene are a cause of cause of retinitis pigmentosa type 45. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2013],

Gene Name: CNGB1

Protein Name: Cyclic nucleotide-gated cation channel beta-1

Molecular Weight: 102 kDa

Gene ID: 1258

OMIM: 600724

UniProt: Q14028

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling, Phototransduction