DOCK1 antibody (AA 1661-1710)

Catalog No. ABIN1534823

The Rabbit Polyclonal anti-DOCK1 antibody (ABIN1534823) specifically detects DOCK1 in WB and ELISA. The antibody is reactive with Human and Mouse samples.

Quick Overview for DOCK1 antibody (AA 1661-1710) (ABIN1534823)

Target: DOCK1 (Dedicator of Cytokinesis 1 (DOCK1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DOCK1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-DOCK1 Antibody

Binding Specificity: AA 1661-1710

Purpose: DOCK 180 Antibody

Specificity: DOCK 180 Polyclonal Antibody detects endogenous levels of DOCK 180 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human DOCK1. AA range:1661-1710

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. ELISA: 1:40000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for DOCK1

Target: DOCK1 (Dedicator of Cytokinesis 1 (DOCK1))

Alternative Name: DOCK1

Background:

Synonyms: DOCK1, Dedicator of cytokinesis protein 1, 180 kDa protein downstream of CRK, DOCK180

Background: This gene encodes a member of the dedicator of cytokinesis protein family. Dedicator of cytokinesis proteins act as guanine nucleotide exchange factors for small Rho family G proteins. The encoded protein regulates the small GTPase Rac, thereby influencing several biological processes, including phagocytosis and cell migration. Overexpression of this gene has also been associated with certain cancers. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2014],

Gene Name: DOCK1

Protein Name: Dedicator of cytokinesis protein 1

Molecular Weight: 215 kDa

Gene ID: 1793

OMIM: 601403

UniProt: Q14185

Pathways: Signaling of Hepatocyte Growth Factor Receptor