POLE antibody (AA 1261-1310)

Catalog No. ABIN1534837

The Rabbit Polyclonal anti-POLE antibody is suitable to detect POLE in samples from Human and Rat. It has been validated for ELISA and IHC.

Quick Overview for POLE antibody (AA 1261-1310) (ABIN1534837)

Target: POLE (Polymerase (DNA Directed), Epsilon, Catalytic Subunit (POLE))

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This POLE antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Product Details anti-POLE Antibody

Binding Specificity: AA 1261-1310

Specificity:

POLE1 Antibody detects endogenous levels of total POLE1 protein.

Purification: The antibody was purified from rabbit antiserum by affinity-chromatography using immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human POLE1.

Isotype: IgG

Application Details

Application Notes: IHC: 1:50~1:100 ELISA: 1:40000

Comment:

Unigene-Number: Hs.524871 (NCBI Gene Symbol: DPOE1)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable at -20°C for at least 1 year.

Expiry Date: 12 months

Target Details for POLE

Target: POLE (Polymerase (DNA Directed), Epsilon, Catalytic Subunit (POLE))

Alternative Name: POLE1

Background:

Synonyms: DNA polymerase epsilon catalytic subunit A, DNA polymerase II subunit A

NCBI Gene Symbol: DPOE1

Molecular Weight: 261 kDa

Gene ID: 5426

OMIM: 174762

UniProt: Q07864

Pathways: Telomere Maintenance, DNA Damage Repair, Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA