EIF2AK1 antibody (AA 571-620)

Catalog No. ABIN1534897

The Rabbit Polyclonal anti-EIF2AK1 antibody is suitable to detect EIF2AK1 in samples from Human, Mouse and Monkey. It has been validated for WB, ELISA, IHC and IF.

Quick Overview for EIF2AK1 antibody (AA 571-620) (ABIN1534897)

Target: EIF2AK1 (Eukaryotic Translation Initiation Factor 2-alpha Kinase 1 (EIF2AK1))

Reactivity: Human, Mouse, Monkey

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EIF2AK1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-EIF2AK1 Antibody

Binding Specificity: AA 571-620

Purpose: HRI Antibody

Specificity: HRI Polyclonal Antibody detects endogenous levels of HRI protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human EIF2AK1. AA range:571-620

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. IHC: 1:100-300 ELISA: 1:20000. IF 1:100-300 Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for EIF2AK1

Target: EIF2AK1 (Eukaryotic Translation Initiation Factor 2-alpha Kinase 1 (EIF2AK1))

Alternative Name: EIF2AK1

Background:

Synonyms: EIF2AK1, HRI, KIAA1369, Eukaryotic translation initiation factor 2-alpha kinase 1, Heme-controlled repressor, HCR, Heme-regulated eukaryotic initiation factor eIF-2-alpha kinase, Heme-regulated inhibitor, Hemin-sensitive initiation factor 2

Background: The protein encoded by this gene acts at the level of translation initiation to downregulate protein synthesis in response to stress. The encoded protein is a kinase that can be inactivated by hemin. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008],

Gene Name: EIF2AK1

Protein Name: Eukaryotic translation initiation factor 2-alpha kinase 1

Molecular Weight: 71 kDa

Gene ID: 27102

UniProt: Q9BQI3

Pathways: Hepatitis C