FOLR1 antibody (AA 41-90)

Catalog No. ABIN1534907

The Rabbit Polyclonal anti-FOLR1 antibody (ABIN1534907) specifically detects FOLR1 in WB and ELISA. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for FOLR1 antibody (AA 41-90) (ABIN1534907)

Target: FOLR1 (Folate Receptor 1 (Adult) (FOLR1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FOLR1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-FOLR1 Antibody

Binding Specificity: AA 41-90

Purpose: FR-α Antibody

Specificity: FR-α Polyclonal Antibody detects endogenous levels of FR-α protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human FOLR1. AA range:41-90

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. ELISA: 1:5000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for FOLR1

Target: FOLR1 (Folate Receptor 1 (Adult) (FOLR1))

Alternative Name: FOLR1

Background:

Synonyms: FOLR1, FOLR, Folate receptor alpha, FR-alpha, Adult folate-binding protein, FBP, Folate receptor 1, Folate receptor, adult, KB cells FBP, Ovarian tumor-associated antigen MOv18

Background: The protein encoded byThis gene is a member of the folate receptor family. Members of this gene family bind folic acid and its reduced derivatives, and transport 5-methyltetrahydrofolate into cells. This gene product is a secreted protein that either anchors to membranes via a glycosyl-phosphatidylinositol linkage or exists in a soluble form. Mutations in this gene have been associated with neurodegeneration due to cerebral folate transport deficiency. Due to the presence of two promoters, multiple transcription start sites, and alternative splicing, multiple transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Oct 2009],

Gene Name: FOLR1

Protein Name: Folate receptor alpha

Molecular Weight: 29 kDa

Gene ID: 2348

OMIM: 136430

UniProt: P15328

Pathways: Dicarboxylic Acid Transport