GABRD antibody (AA 141-190)

Catalog No. ABIN485541

The Rabbit Polyclonal anti-GABRD antibody (ABIN485541) specifically detects GABRD in WB, IHC, ELISA and IF. The antibody is reactive with Human, Rat and Mouse samples.

Quick Overview for GABRD antibody (AA 141-190) (ABIN485541)

Target: GABRD (GABA A Receptor delta (GABRD))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GABRD antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Product Details anti-GABRD Antibody

Binding Specificity: AA 141-190

Purpose: GABAA Rδ Antibody

Specificity: GABAA Rδ Polyclonal Antibody detects endogenous levels of GABAA Rδ protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human GABRD. AA range:141-190

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for GABRD

Target: GABRD (GABA A Receptor delta (GABRD))

Alternative Name: GABRD

Background:

Synonyms: GABRD, Gamma-aminobutyric acid receptor subunit delta, GABA(A) receptor subunit delta

Background: Gamma-aminobutyric acid (GABA) is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. The GABA-A receptor is generally pentameric and there are five types of subunits: alpha, beta, gamma, delta, and rho.This gene encodes the delta subunit. Mutations in this gene have been associated with susceptibility to generalized epilepsy with febrile seizures, type 5. Alternatively spliced transcript variants have been described for this gene, but their biological validity has not been determined. [provided by RefSeq, Jul 2008],

Gene Name: GABRD

Protein Name: Gamma-aminobutyric acid receptor subunit delta

Molecular Weight: 50 kDa

Gene ID: 2563

OMIM: 137163

UniProt: O14764