TSTA3 antibody (AA 221-270)

Catalog No. ABIN1534938

This Rabbit Polyclonal antibody specifically detects TSTA3 in WB and ELISA. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for TSTA3 antibody (AA 221-270) (ABIN1534938)

Target: TSTA3 (Tissue Specific Transplantation Antigen P35B (TSTA3))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TSTA3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-TSTA3 Antibody

Binding Specificity: AA 221-270

Purpose: FX Antibody

Specificity: FX Polyclonal Antibody detects endogenous levels of FX protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human TSTA3. AA range:221-270

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. ELISA: 1:20000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for TSTA3

Target: TSTA3 (Tissue Specific Transplantation Antigen P35B (TSTA3))

Alternative Name: TSTA3

Background:

Synonyms: TSTA3, SDR4E1, GDP-L-fucose synthase, GDP-4-keto-6-deoxy-D-mannose-3, 5-epimerase-4-reductase, Protein FX, Red cell NADP(H)-binding protein, Short-chain dehydrogenase/reductase family 4E member 1

Background: Tissue specific transplantation antigen P35B is a NADP(H)-binding protein. It catalyze the two-step epimerase and the reductase reactions in GDP-D-mannose metabolism, converting GDP-4-keto-6-D-deoxymannose to GDP-L-fucose. GDP-L-fucose is the substrate of several fucosyltransferases involved in the expression of many glycoconjugates, including blood group ABH antigens and developmental adhesion antigens. Mutations in this gene may cause leukocyte adhesion deficiency, type II. [provided by RefSeq, Jul 2008],

Gene Name: TSTA3

Protein Name: GDP-L-fucose synthase

Molecular Weight: 35 kDa

Gene ID: 7264

OMIM: 137020

UniProt: Q13630