GUF1 antibody (AA 421-470)

Catalog No. ABIN1534964

The Rabbit Polyclonal anti-GUF1 antibody (ABIN1534964) specifically detects GUF1 in ELISA, IHC and IF. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for GUF1 antibody (AA 421-470) (ABIN1534964)

Target: GUF1 (GUF1 GTPase Homolog (GUF1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GUF1 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-GUF1 Antibody

Binding Specificity: AA 421-470

Purpose: GUF1 Antibody

Specificity: GUF1 Polyclonal Antibody detects endogenous levels of GUF1 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human GUF1. AA range:421-470

Isotype: IgG

Application Details

Application Notes: IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for GUF1

Target: GUF1 (GUF1 GTPase Homolog (GUF1))

Alternative Name: GUF1

Background:

Synonyms: GUF1, Translation factor GUF1, mitochondrial, Elongation factor 4 homolog, EF-4, GTPase GUF1, Ribosomal back-translocase

Background: This gene encodes a GTPase that triggers back-translocation of the elongating ribosome during mitochondrial protein synthesis. The protein contains a highly conserved C-terminal domain not found in other GTPases that facilitates tRNA binding. The encoded protein is thought to prevent misincorporation of amino acids in stressful, suboptimal conditions. An allelic variant in this gene has been associated with early infantile epileptic encephalopathy-40. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2016],

Gene Name: GUF1

Protein Name: Translation factor GUF1 mitochondrial

Molecular Weight: 74 kDa

Gene ID: 60558

UniProt: Q8N442