HLA-DOA antibody (AA 71-120)

Catalog No. ABIN1534980

This Rabbit Polyclonal antibody specifically detects HLA-DOA in WB, ELISA, IHC and IF. It exhibits reactivity toward Human.

Quick Overview for HLA-DOA antibody (AA 71-120) (ABIN1534980)

Target: HLA-DOA (HLA Class II DO alpha (HLA-DOA))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HLA-DOA antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-HLA-DOA Antibody

Binding Specificity: AA 71-120

Purpose: HLA-DOα Antibody

Specificity: HLA-DOα Polyclonal Antibody detects endogenous levels of HLA-DOα protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human HLA-DOA. AA range:71-120

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for HLA-DOA

Target: HLA-DOA (HLA Class II DO alpha (HLA-DOA))

Alternative Name: HLA-DOA

Background:

Synonyms: HLA-DOA, HLA-DNA, HLA-DZA, HLA class II histocompatibility antigen, DO alpha chain, MHC DN-alpha, MHC DZ alpha, MHC class II antigen DOA

Background: HLA-DOA belongs to the HLA class II alpha chain paralogues. HLA-DOA forms a heterodimer with HLA-DOB. The heterodimer, HLA-DO, is found in lysosomes in B cells and regulates HLA-DM-mediated peptide loading on MHC class II molecules. In comparison with classical HLA class II molecules, this gene exhibits very little sequence variation, especially at the protein level. [provided by RefSeq, Jul 2008],

Gene Name: HLA-DOA

Protein Name: HLA class II histocompatibility antigen DO alpha chain

Molecular Weight: 27 kDa

Gene ID: 3111

OMIM: 142930

UniProt: P06340

Pathways: Human Leukocyte Antigen (HLA) in Adaptive Immune Response