HOXA11/D11 antibody (AA 216-265)

Catalog No. ABIN1534981

The Rabbit Polyclonal anti-HOXA11/D11 antibody is suitable to detect HOXA11/D11 in samples from Human and Mouse. It has been validated for WB, IF, ELISA and IHC.

Quick Overview for HOXA11/D11 antibody (AA 216-265) (ABIN1534981)

Target: HOXA11/D11 (HOXA11 + HOXD11) (Homeobox A11/D11 (HOXA11 + HOXD11))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HOXA11/D11 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), ELISA, Immunohistochemistry (IHC)

Product Details anti-HOXA11/D11 Antibody

Binding Specificity: AA 216-265

Purpose: HoxA11/D11 Antibody

Specificity: HoxA11/D11 Polyclonal Antibody detects endogenous levels of HoxA11/D11 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human HOXA11/D11. AA range:216-265

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for HOXA11/D11

Target: HOXA11/D11 (HOXA11 + HOXD11) (Homeobox A11/D11 (HOXA11 + HOXD11))

Background:

Synonyms: HOXA11, HOX1I, Homeobox protein Hox-A11, Homeobox protein Hox-1I, HOXD11, HOX4F, Homeobox protein Hox-D11, Homeobox protein Hox-4F

Background: In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. This gene is involved in the regulation of uterine development and is required for female fertility. Mutations in this gene can cause radio-ulnar synostosis with amegakaryocytic thrombocytopenia. [provided by RefSeq, Jul 2008],

Gene Name: HOXA11/HOXD11

Protein Name: Homeobox protein Hox-A11/D11

Molecular Weight: 34 kDa

Gene ID: 3207, 3237

OMIM: 142958

UniProt: P31270