HOXA11/D11 antibody (AA 190-270)

Catalog No. ABIN7215314

The Rabbit Polyclonal anti-HOXA11/D11 antibody is suitable to detect HOXA11/D11 in samples from Human and Mouse. It has been validated for WB, IF, ELISA and IHC.

Quick Overview for HOXA11/D11 antibody (AA 190-270) (ABIN7215314)

Target: HOXA11/D11 (HOXA11 + HOXD11) (Homeobox A11/D11 (HOXA11 + HOXD11))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HOXA11/D11 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), ELISA, Immunohistochemistry (IHC)

Product Details anti-HOXA11/D11 Antibody

Binding Specificity: AA 190-270

Purpose: Rabbit Anti-HoxA11/D11 Polyclonal Antibody

Specificity: HoxA11/D11 Polyclonal Antibody detects endogenous levels of HoxA11/D11 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the C-terminal region of human HoxA11/D11 at AA range: 190-270

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,IF 1:200-1:1000,ELISA 1:20000,Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for HOXA11/D11

Target: HOXA11/D11 (HOXA11 + HOXD11) (Homeobox A11/D11 (HOXA11 + HOXD11))

Alternative Name: HoxA11/D11

Background: HOXA11, HOX1I, Homeobox protein Hox-A11, Homeobox protein Hox-1I, HOXD11, HOX4F, Homeobox protein Hox-D11, Homeobox protein Hox-4FIn vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. HOXA11 is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. HOXA11 is involved in the regulation of uterine development and is required for female fertility. Mutations in this gene can cause radio-ulnar synostosis with amegakaryocytic thrombocytopenia.

Molecular Weight: 28kD

Gene ID: 3207, 3237

UniProt: P31270, P31277