HOXD10 antibody (AA 291-340)

Catalog No. ABIN1534984

The Rabbit Polyclonal anti-HOXD10 antibody is suitable to detect HOXD10 in samples from Human and Mouse. It has been validated for WB and ELISA.

Quick Overview for HOXD10 antibody (AA 291-340) (ABIN1534984)

Target: HOXD10 (Homeobox D10 (HOXD10))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HOXD10 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-HOXD10 Antibody

Binding Specificity: AA 291-340

Purpose: HoxD10 Antibody

Specificity: HoxD10 Polyclonal Antibody detects endogenous levels of HoxD10 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human HOXD10. AA range:291-340

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. ELISA: 1:40000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for HOXD10

Target: HOXD10 (Homeobox D10 (HOXD10))

Alternative Name: HOXD10

Background:

Synonyms: HOXD10; HOX4D; HOX4E; Homeobox protein Hox-D10; Homeobox protein Hox-4D; Homeobox protein Hox-4E

Background: This gene is a member of the Abd-B homeobox family and encodes a protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox D genes located on chromosome 2. The encoded nuclear protein functions as a sequence-specific transcription factor that is expressed in the developing limb buds and is involved in differentiation and limb development. Mutations in this gene have been associated with Wilm's tumor and congenital vertical talus (also known as "rocker-bottom foot" deformity or congenital convex pes valgus) and/or a foot deformity resembling that seen in Charcot-Marie-Tooth disease. [provided by RefSeq, Jul 2008],

Gene Name: HOXD10

Protein Name: Homeobox protein Hox-D10

Molecular Weight: 38 kDa

Gene ID: 3236

OMIM: 142984

UniProt: P28358