IQCB1 antibody (AA 431-480)

Catalog No. ABIN1534993

The Rabbit Polyclonal anti-IQCB1 antibody is suitable to detect IQCB1 in samples from Human, Mouse and Rat. It has been validated for WB, ELISA, IHC and IF.

Quick Overview for IQCB1 antibody (AA 431-480) (ABIN1534993)

Target: IQCB1 (IQ Motif Containing B1 (IQCB1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IQCB1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-IQCB1 Antibody

Binding Specificity: AA 431-480

Purpose: Nephrocystin-5 Antibody

Specificity: Nephrocystin-5 Polyclonal Antibody detects endogenous levels of Nephrocystin-5 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human IQCB1. AA range:431-480

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for IQCB1

Target: IQCB1 (IQ Motif Containing B1 (IQCB1))

Alternative Name: IQCB1

Background:

Synonyms: IQCB1, KIAA0036, NPHP5, OK/SW-cl.85, IQ calmodulin-binding motif-containing protein 1, Nephrocystin-5, p53 and DNA damage-regulated IQ motif protein, PIQ

Background: This gene encodes a nephrocystin protein that interacts with calmodulin and the retinitis pigmentosa GTPase regulator protein. The encoded protein has a central coiled-coil region and two calmodulin-binding IQ domains. It is localized to the primary cilia of renal epithelial cells and connecting cilia of photoreceptor cells. The protein is thought to play a role in ciliary function. Defects in this gene result in Senior-Loken syndrome type 5. Alternative splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 6. [provided by RefSeq, Jan 2016],

Gene Name: IQCB1

Protein Name: IQ calmodulin-binding motif-containing protein 1

Molecular Weight: 68 kDa

Gene ID: 9657

OMIM: 609237

UniProt: Q15051