NACAD antibody (AA 350-430)

Catalog No. ABIN7220650

The Rabbit Polyclonal anti-NACAD antibody is suitable to detect NACAD in samples from Human and Mouse. It has been validated for WB and IHC.

Quick Overview for NACAD antibody (AA 350-430) (ABIN7220650)

Target: NACAD (NAC alpha Domain Containing (NACAD))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NACAD antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-NACAD Antibody

Binding Specificity: AA 350-430

Purpose: Rabbit Anti-NACAD Polyclonal Antibody

Specificity: NACAD Polyclonal Antibody detects endogenous levels of NACAD protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human NACAD at AA range: 350-430

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,IHC 1:50-300

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for NACAD

Target: NACAD (NAC alpha Domain Containing (NACAD))

Alternative Name: NACAD

Background: NACAD, KIAA0363, NAC-alpha domain-containing protein 1May prevent inappropriate targeting of non-secretory polypeptides to the endoplasmic reticulum (ER). May bind to nascent polypeptide chains as they emerge from the ribosome and block their interaction with the signal recognition particle (SRP), which normally targets nascent secretory peptides to the ER. May also reduce the inherent affinity of ribosomes for protein translocation sites in the ER membrane (M sites).

Molecular Weight: 140kD

Gene ID: 23148

UniProt: O15069