NCR1 antibody (AA 145-194)

Catalog No. ABIN1535078

The Rabbit Polyclonal anti-NCR1 antibody (ABIN1535078) specifically detects NCR1 in WB and ELISA. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for NCR1 antibody (AA 145-194) (ABIN1535078)

Target: NCR1 (Natural Cytotoxicity Triggering Receptor 1 (NCR1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NCR1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-NCR1 Antibody

Binding Specificity: AA 145-194

Purpose: NKp46 Antibody

Specificity: NKp46 Polyclonal Antibody detects endogenous levels of NKp46 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human NCR1. AA range:145-194

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for NCR1

Target: NCR1 (Natural Cytotoxicity Triggering Receptor 1 (NCR1))

Alternative Name: NCR1

Background:

Synonyms: NCR1, LY94, Natural cytotoxicity triggering receptor 1, Lymphocyte antigen 94 homolog, NK cell-activating receptor, Natural killer cell p46-related protein, NK-p46, NKp46, hNKp46, CD antigen CD335

Background: function:Cytotoxicity-activating receptor that may contribute to the increased efficiency of activated natural killer (NK) cells to mediate tumor cell lysis.,PTM:N-glycosylated.,PTM:O-glycosylated.,similarity:Belongs to the natural cytotoxicity receptor (NCR) family.,similarity:Contains 2 Ig-like (immunoglobulin-like) domains.,subunit:Interacts with CD3Z and FCER1G.,tissue specificity:Selectively expressed by both resting and activated NK cells.,

Gene Name: NCR1

Protein Name: Natural cytotoxicity triggering receptor 1

Molecular Weight: 34 kDa

Gene ID: 9437

OMIM: 604530

UniProt: O76036

Pathways: Regulation of Leukocyte Mediated Immunity