PEX3 antibody (AA 12-61)

Catalog No. ABIN1535149

The Rabbit Polyclonal anti-PEX3 antibody is suitable to detect PEX3 in samples from Human, Mouse and Rat. It has been validated for WB, IHC and ELISA.

Quick Overview for PEX3 antibody (AA 12-61) (ABIN1535149)

Target: PEX3 (Peroxisomal Biogenesis Factor 3 (PEX3))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PEX3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Product Details anti-PEX3 Antibody

Binding Specificity: AA 12-61

Purpose: Peroxin 3 Antibody

Specificity: Peroxin 3 Polyclonal Antibody detects endogenous levels of Peroxin 3 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human PEX3. AA range:12-61

Isotype: IgG

Application Details

Application Notes: WB 1:500-2000,IHC 1:50-300, ELISA 2000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for PEX3

Target: PEX3 (Peroxisomal Biogenesis Factor 3 (PEX3))

Alternative Name: PEX3

Background:

Synonyms: PEX3, Peroxisomal biogenesis factor 3, Peroxin-3, Peroxisomal assembly protein PEX3

Background: The product of this gene is involved in peroxisome biosynthesis and integrity. It assembles membrane vesicles before the matrix proteins are translocated. Peroxins (PEXs) are proteins that are essential for the assembly of functional peroxisomes. The peroxisome biogenesis disorders (PBDs) are a group of genetically heterogeneous autosomal recessive, lethal diseases characterized by multiple defects in peroxisome function. The peroxisomal biogenesis disorders are a heterogeneous group with at least 14 complementation groups and with more than 1 phenotype being observed in cases falling into particular complementation groups. Although the clinical features of PBD patients vary, cells from all PBD patients exhibit a defect in the import of one or more classes of peroxisomal matrix proteins into the organelle. Defects in this gene are a cause Zellweger syndrome (ZWS). [provided by RefSeq, Oct 20

Gene Name: PEX3

Protein Name: Peroxisomal biogenesis factor 3

Molecular Weight: 42 kDa

Gene ID: 8504

OMIM: 214100

UniProt: P56589