FNTB antibody (AA 255-304)

Catalog No. ABIN1535214

This Rabbit Polyclonal antibody specifically detects FNTB in WB and ELISA. It exhibits reactivity toward Human, Rat and Mouse.

Quick Overview for FNTB antibody (AA 255-304) (ABIN1535214)

Target: FNTB (Farnesyltransferase subunit beta (FNTB))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FNTB antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-FNTB Antibody

Binding Specificity: AA 255-304

Purpose: FTβ Antibody

Specificity: FTβ Polyclonal Antibody detects endogenous levels of FTβ protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human FNTB. AA range:255-304

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. ELISA: 1:40000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for FNTB

Target: FNTB (Farnesyltransferase subunit beta (FNTB))

Alternative Name: FNTB

Background:

Synonyms: FNTB, Protein farnesyltransferase subunit beta, FTase-beta, CAAX farnesyltransferase subunit beta, Ras proteins prenyltransferase subunit beta

Background: catalytic activity:Farnesyl diphosphate + protein-cysteine = S-farnesyl protein + diphosphate.,cofactor:Binds 1 zinc ion per subunit.,function:Catalyzes the transfer of a farnesyl moiety from farnesyl pyrophosphate to a cysteine at the fourth position from the C-terminus of several proteins. The beta subunit is responsible for peptide-binding.,similarity:Belongs to the protein prenyltransferase subunit beta family.,similarity:Contains 5 PFTB repeats.,subunit:Heterodimer of an alpha and a beta subunit.,

Gene Name: FNTB

Protein Name: Protein farnesyltransferase subunit beta

Molecular Weight: 48 kDa

Gene ID: 2342

OMIM: 134636

UniProt: P49356