PPP1R3C antibody (AA 44-93)

Catalog No. ABIN1535223

This Rabbit Polyclonal antibody specifically detects PPP1R3C in WB, ELISA, IHC and IF. It exhibits reactivity toward Human and Monkey.

Quick Overview for PPP1R3C antibody (AA 44-93) (ABIN1535223)

Target: PPP1R3C (Protein Phosphatase 1, Regulatory Subunit 3C (PPP1R3C))

Reactivity: Human, Monkey

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PPP1R3C antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-PPP1R3C Antibody

Binding Specificity: AA 44-93

Purpose: PTG Antibody

Specificity: PTG Polyclonal Antibody detects endogenous levels of PTG protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human PPP1R3C. AA range:44-93

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for PPP1R3C

Target: PPP1R3C (Protein Phosphatase 1, Regulatory Subunit 3C (PPP1R3C))

Alternative Name: PPP1R3C

Background:

Synonyms: PPP1R3C, PPP1R5, Protein phosphatase 1 regulatory subunit 3C, Protein phosphatase 1 regulatory subunit 5, PP1 subunit R5, Protein targeting to glycogen, PTG

Background: This gene encodes a carbohydrate binding protein that is a subunit of the protein phosphatase 1 (PP1) complex. PP1 catalyzes reversible protein phosphorylation, which is important in a wide range of cellular activities. The encoded protein affects glycogen biosynthesis by activating glycogen synthase and limiting glycogen breakdown by reducing glycogen phosphorylase activity. DNA hypermethylation of this gene has been found in colorectal cancer patients. The encoded protein also interacts with the laforin protein, which is a protein tyrosine phosphatase implicated in Lafora disease. [provided by RefSeq, Sep 2016],

Gene Name: PPP1R3C

Protein Name: Protein phosphatase 1 regulatory subunit 3C

Molecular Weight: 36 kDa

Gene ID: 5507

OMIM: 602999

UniProt: Q9UQK1

Pathways: Cellular Glucan Metabolic Process, Regulation of Carbohydrate Metabolic Process