Arhgef9 antibody (AA 399-448)

Catalog No. ABIN1535302

The Rabbit Polyclonal anti-Arhgef9 antibody is suitable to detect Arhgef9 in samples from Human, Rat and Mouse. It has been validated for IHC, ELISA and IF.

Quick Overview for Arhgef9 antibody (AA 399-448) (ABIN1535302)

Target: Arhgef9 (Cdc42 Guanine Nucleotide Exchange Factor (GEF) 9 (Arhgef9))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Arhgef9 antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Product Details anti-Arhgef9 Antibody

Binding Specificity: AA 399-448

Purpose: ARHGEF9 Antibody

Specificity: ARHGEF9 Polyclonal Antibody detects endogenous levels of ARHGEF9 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human ARHGEF9. AA range:399-448

Isotype: IgG

Application Details

Application Notes: IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for Arhgef9

Target: Arhgef9 (Cdc42 Guanine Nucleotide Exchange Factor (GEF) 9 (Arhgef9))

Alternative Name: ARHGEF9

Background:

Synonyms: ARHGEF9, ARHDH9, KIAA0424, Rho guanine nucleotide exchange factor 9, Collybistin, PEM-2 homolog, Rac/Cdc42 guanine nucleotide exchange factor 9

Background: The protein encoded by this gene is a Rho-like GTPase that switches between the active (GTP-bound) state and inactive (GDP-bound) state to regulate CDC42 and other genes. Defects in this gene are a cause of startle disease with epilepsy (STHEE), also known as hyperekplexia with epilepsy. Three transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Mar 2010],

Gene Name: ARHGEF9

Protein Name: Rho guanine nucleotide exchange factor 9

Molecular Weight: 60 kDa

Gene ID: 23229

OMIM: 300429

UniProt: O43307

Pathways: Neurotrophin Signaling Pathway