TNXB antibody (AA 1761-1810)

Catalog No. ABIN1535407

The Rabbit Polyclonal anti-TNXB antibody is suitable to detect TNXB in samples from Human, Mouse and Rat. It has been validated for IHC, ELISA and IF.

Quick Overview for TNXB antibody (AA 1761-1810) (ABIN1535407)

Target: TNXB (Tenascin XB (TNXB))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TNXB antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Product Details anti-TNXB Antibody

Binding Specificity: AA 1761-1810

Purpose: Tenascin-X Antibody

Specificity: Tenascin-X Polyclonal Antibody detects endogenous levels of Tenascin-X protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human TNXB. AA range:1761-1810

Isotype: IgG

Application Details

Application Notes: IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for TNXB

Target: TNXB (Tenascin XB (TNXB))

Alternative Name: TNXB

Background:

Synonyms: TNXB; HXBL; TNX; TNXB1; TNXB2; XB; Tenascin-X; TN-X; Hexabrachion-like protein

Background: This gene encodes a member of the tenascin family of extracellular matrix glycoproteins. The tenascins have anti-adhesive effects, as opposed to fibronectin which is adhesive. This protein is thought to function in matrix maturation during wound healing, and its deficiency has been associated with the connective tissue disorder Ehlers-Danlos syndrome. This gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. It is one of four genes in this cluster which have been duplicated. The duplicated copy of this gene is incomplete and is a pseudogene which is transcribed but does not encode a protein. The structure of this gene is unusual in that it overlaps the CREBL1 and CYP21A2 genes at its 5' and 3' ends, respectively. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],

Gene Name: TNXB

Protein Name: Tenascin-X

Molecular Weight: 464 kDa

Gene ID: 7148

OMIM: 606408

UniProt: P22105